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Medical Minute: Osteoporosis

 

I had a proactive health screening a few months ago and was shocked when the nurse told me I needed to follow up about my bone density. Surely I’m too young for this I thought! This month, our friends at Brookwood Medical Center share some knowledge about Osteoporosis. It’s a disease in which there is a loss of bone mass and destruction of bone tissue. This process causes weakening of the bones and makes them more likely to break. The bones most often affected are the hips, spine, and wrists.

Osteoporosis affects over 10 million Americans over the age of 50, with women four times more likely to develop osteoporosis than men. Another 34 million  Americans over the age of 50 have low bone mass (osteopenia) and therefore have an increased risk for osteoporosis. Estrogen deficiency is one of the main causes of bone loss in women during and after menopause. Women may lose up to 20 percent of their bone mass in the five to seven years following menopause.

Although the exact medical cause for osteoporosis is unknown, a number of factors contribute to osteoporosis, including the following:

  • Aging. Bones become less dense and weaker with age.
  • Race. White and Asian women are most at risk, although all races may develop the disease.
  • Body weight. Obesity is associated with a higher bone mass, therefore people who weigh less and have less muscle are more at risk for developing osteoporosis.
  • Lifestyle factors. The following lifestyle factors may increase a person’s risk of osteoporosis:
    • Physical inactivity
    • Caffeine
    • Excessive alcohol use
    • Smoking
    • Dietary calcium and vitamin D deficiency
  • Certain medications
  • Family history of bone disease

What are the symptoms of osteoporosis?

Osteoporosis is often called the silent disease because people with osteoporosis may not develop any symptoms. Some may have pain in their bones and muscles, particularly in their back. Occasionally, a collapsed vertebra may cause severe pain, decrease in height, or deformity in the spine.

The symptoms of osteoporosis may resemble other bone disorders or medical problems. Always consult your doctor for a diagnosis.

How osteoporosis is diagnosed:

In addition to a complete personal and family medical history and physical examination, diagnostic procedures for osteoporosis may include the following:

  • X-rays (skeletal). A diagnostic test that uses invisible electromagnetic energy beams to produce images of internal tissues, bones, and organs onto film.
  • Bone density test (also called bone densitometry). Measurement of the mass of bone in relation to its volume to determine the risk of developing osteoporosis.
  • Blood tests. These tests are done to measure serum calcium and potassium levels.
  • FRAX score. A score given to estimate the risk of a fracture within 10 years. The score uses the results of a bone densitometry test as well as other individual factors.

The effects of this disease can best be managed with early diagnosis and treatment.

Treatment for osteoporosis:

Specific treatment for osteoporosis will be determined by your doctor based on:

  • Your age, overall health, and medical history
  • Extent of the disease
  • Your tolerance for specific medications, procedures, or therapies
  • Expectations for the course of the disease
  • Your opinion or preference

The goals of managing osteoporosis are to decrease pain, prevent fractures, and minimize further bone loss. Some of the methods used to treat osteoporosis are also the methods to help prevent it from developing, including the following:

  • Maintain an appropriate body weight.
  • Increase walking and other weight-bearing exercises.
  • Minimize caffeine and alcohol consumption.
  • Stop smoking.
  • Maintain an adequate intake of calcium through diet and supplements. Vitamin D is also necessary because it facilitates the absorption of calcium.
  • Prevent falls in the elderly to prevent fractures (for example, install hand railings, or assistive devices in the bathroom or shower).
  • Consult your doctor regarding a medication regimen.

For postmenopausal osteoporosis in women, the FDA has approved the following medications to maintain bone health:

  • Estrogen replacement therapy (ERT) and hormone replacement therapy (HRT). ERT has proven to reduce bone loss, increase bone density, and reduce the risk of hip and spinal fractures in postmenopausal women. However, a woman considering ERT should consult her doctor, as the research conducted by the National Heart, Lung, and Blood Institute of the National Institutes of Health found several important health risks associated with this therapy. For many women, the risks of ERT outweigh the benefits.
  • Alendronate sodium (Fosamax). This medication, from a group of medications called bisphosphonates, reduces bone loss, increases bone density, and reduces the risk of fractures.
  • Risedronate sodium (Actonel). This medication is also from the bisphosphonate family and has similar effects as alendronate.
  • Ibandronate sodium (Boniva). This medication is a type of bisphosphonate that is taken once a month. It works by slowing the loss of bone, which may increase bone mass.
  • Raloxifene (Evista). This medication is from a new group of medications called selective estrogen receptor modulators (SERMs) that help to prevent bone loss.
  • Parathyroid hormone (Fortéo). This medication is a form of parathyroid hormone, teriparatide, and is approved to treat postmenopausal women and men who are at high risk for fractures. It helps form bone.
  • Denosumab (Prolia, Xgeva). This medication is a monoclonal antibody given by injection under the skin and is approved for women with osteoporosis at high risk for fractures, as well as for women who are being treated with cancer medications that can weaken bones.

Rehabilitation for osteoporosis:

An osteoporosis rehabilitation program is designed to meet the needs of the individual patient, depending on the type and severity of the disease. Active involvement of the patient and family is vital to the success of the program.

The goal of rehabilitation is to help the patient to return to the highest level of function and independence possible, while improving the overall quality of life–physically, emotionally, and socially. The focus of rehabilitation is to decrease pain, help prevent fractures, and minimize further bone loss.

In order to help reach these goals, osteoporosis rehabilitation programs may include the following:

  • Exercise programs and conditioning to increase weight bearing and physical fitness
  • Pain management techniques
  • Nutritional counseling to improve calcium and vitamin D intake and decrease caffeine and alcohol intake
  • Use of assistive devices to improve safety at home patient and family education, especially prevention of falls

 

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